Management of Uterine Leiomyomata and Adenomyosis

Ahmed Ali Mahmoud

Status: Unknown

Conditions: Abnormal Uterine Bleeding

Treatments: Drug: Norethisterone acetate

Study type: Observational

Funder types: Other

Identifiers

NCT05153928

12091984

Details and patient eligibility

About

1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination
2. to evaluate the efficacy of norethisterone in the treatment of symptomatic adenomyosis and leiomyoma

Full description

The aim of the present study is:

1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination
2. to evaluate the efficacy of norethisterone in the treatment of symptomatic adenomyosis and leiomyoma

Enrollment: 100 estimated patients

Sex: Female

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• (1) age≥30 years; (4) dysmenorrhea, adenomyosis-associated chronic pain, and/or menorrhagia.

(3) regular menstrual cycles before administration of norethisterone; (4) no other treatment for adenomyosis/leiomyomatosis at least for 3 months biopsies and histopathology for operated patients;

Exclusion criteria

• (1) pregnant and/or breast-feeding women (2) patients with a ovarian neoplasm, benign ovarian cyst including endometrioma, pelvic inflammatory disease or other endocrine diseases.

Trial design

100 participants in 2 patient groups

fibroid cases

Description:

Norethisterone acetate for 5 months

Treatment:

Drug: Norethisterone acetate

adenomyosis

Description:

Norethisterone acetate for 5 months

Treatment:

Drug: Norethisterone acetate