Management of Women With BRCA1/2 Mutation

University Hospital Center (CHU)

Status: Completed

Conditions: BRCA2 Mutation; BRCA1 Mutation

Treatments: Behavioral: Questionnaire given to the two groups

Study type: Observational

Funder types: Other

Identifiers

NCT03211611

RECHMPL17_0200

Details and patient eligibility

About

The aim of this study is to determine general practitionners' role in management of women with BRCA1/2 mutation.

This study will be conduct between April 2017 and December 2017 at Montpellier University Hospital on women followed-up in the department of genetics and their general practitionners (GP). Patients and their GP will be called by the investigators and questionnaire will be given to them. Questionnaire includes questions for patients and their GP. The primary endpoint was to determine the rate of GP having sufficient knowledge of the adequate management of patients with BRCA1 / 2 mutation. Adequate knowledge includes : systematic search for a family history of cancer, knowing criteria required to refer women in oncogenetic department, and the ability to respond to patients' questions. Secondary endpoint was to determine women' opinion on their GP : whether or not well managed for their BRCA 1 / 2 mutation.

Full description

PURPOSE: The aim of this study is to determine general practitionners' role in management of women with BRCA1/2 mutation.

METHODS:

This study will be conduct between April 2017 and December 2017 at Montpellier University Hospital on women followed-up in the department of genetics and their general practitionners (GP). Patients and their GP will be called by the investigators and questionnaire will be given to them. Questionnaire includes questions for patients and their GP. The primary endpoint was to determine the rate of GP having sufficient knowledge of the adequate management of patients with BRCA1 / 2 mutation. Adequate knowledge includes : systematic search for a family history of cancer, knowing criteria required to refer women in oncogenetic department, and the ability to respond to patients' questions. Secondary endpoint was to determine women' opinion on their GP : whether or not well managed for their BRCA 1 / 2 mutation.

Enrollment: 600 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria

• Aged over 18
• Women
• Living in France
• Having a medical insurance

Exclusion criteria

• Men
• Dementia
• Non frenchspeaker
• Mental retardation
• Being the subject of a guardianship or tutelage measure

Trial design

600 participants in 2 patient groups

Patients with BRCA ½ mutation

Description:

Women with BRCA 1 / 2 mutation with or without cancer Age over 18

Treatment:

Behavioral: Questionnaire given to the two groups

GP

Description:

GP of the patients with BRCA 1 / 2 mutation

Treatment:

Behavioral: Questionnaire given to the two groups