Management Strategy of Polypoid Lesions of the Gallbladder

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Completed

Conditions: Polyp Gallbladder

Treatments: Other: Non

Study type: Observational

Funder types: Other

Identifiers

NCT04762797

PUMCHTF3

Details and patient eligibility

About

We retrospectively review a single-center cohort of gallbladder polyps from January 2015 to May 2020. Univariate and multivariable analyses were performed to extract potential risky factors of neoplastic polyps. Also, a comparison was conducted between laparoscopic cholecystectomy (LC) and laparoscopic polypectomy (LP) to explore factors affecting surgeons' decision on LC or LP.

Enrollment: 672 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Surgical indications for LC included polyp diameter over 10 millimeters, or polyps accompanied by GB stones, or consideration of neoplastic polyps. Surgical indications for GB-preserving surgery included GB with normal emptying function and polyp diameter smaller than 10 millimeters, or consideration of benign non-neoplastic polyps, or asymptomatic polyps.

Exclusion criteria

Those do not fit for laparoscopic surgery.

Trial design

672 participants in 2 patient groups

Non-neoplastic group

Description:

Gallbladder polyps with pathological diagnosis of cholesterol polyps or inflammatory polyps are classified into "Non-neoplastic group".

Treatment:

Other: Non

Neoplastic group

Description:

Gallbladder polyps pathologically diagnosed as adenocarcinoma, adenoma, adenomyosis, or other malignancies are classified into "Neoplastic group".

Treatment:

Other: Non