Managing Dry Eye in Patients Using Glaucoma Drops

He Eye Hospital

Status: Completed

Conditions: Dry Eye

Treatments: Device: IPL

Study type: Interventional

Funder types: Other

Identifiers

NCT06158984

GLADQSLIP2023

Details and patient eligibility

About

A single center randomized controlled trial on managing dry eye signs and symptoms in patients using anti-glaucoma eye drops.

Full description

To compare the safety and efficacy of IPL therapy on drug-induced dry eye caused by long-term use of anti glaucoma drugs;

Enrollment: 60 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years
• Able and willing to comply with the treatment/follow-up schedule
• Bilateral signs and symptoms of dry eye disease

Exclusion criteria

• Participants with systemic immune-mediated illnesses, such as secondary Sjögren's syndrome or graft-versus-host disease
• Patients using topical medication(s) for the treatment of ocular disorders such as allergic conjunctivitis were excluded from the study.
• Previous ocular surgery or trauma
• 1-month history of blepharal and periorbital skin disease or allergies
• Severe dry eyes with corneal epithelial defect
• Limbic keratitis
• Pterygium
• Corneal neovascularization
• Breastfeeding
• Rheumatic immune systemic diseases
• Herpes zoster infection
• Pregnant women
• Allergic to fluorescein
• Contact lens wearers

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

IPL group

Experimental group

Description:

IPL group will use 2 sessions of IPL therapy, 15 days apart for the management of drug-induced dry eye in glaucoma patients.

Treatment:

Device: IPL

Control group

No Intervention group

Description:

The control group received no treatment