Mannose Binding Lectin Gene Polymorphism Versus Microbial Virulence in the Pathogenesis of Vulvovaginal Candidiasis

Aljazeera Hospital

Status: Unknown

Conditions: Infection

Treatments: Diagnostic Test: blood sample

Study type: Observational

Funder types: Other

Identifiers

NCT04552210

Mannose

Details and patient eligibility

About

The vaginal mucosa is inhabited by both fungal and bacterial microorganisms which normally co-exist with the host in a tightly regulated and commensal manner.

Full description

Nevertheless, under certain circumstances, this co-existence can turn into a pathologic state followed by symptomatic disease

Enrollment: 50 estimated patients

Sex: Female

Ages: 18 to 42 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1. Married females in the reproductive age period. 2. Females complaining of vaginal discharge (whitish and scanty), itching, dyspareunia, pruritis, and signs of vulvovaginitis ie. erythema.

Exclusion criteria

• females who attended the same clinic in the same period, matched the cases regarding the age group, without having Candida infection as confirmed by culture of vaginal swabs.