Mantram Repetition to Manage PTSD in Veterans

US Department of Veterans Affairs (VA)

Status: Completed

Conditions: Stress Disorders, Post Traumatic

Treatments: Other: Usual care consisting of medication and case management; Behavioral: Mantram Repetition Program (MRP) plus Usual Care

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT00120627

NRI 04-041

Details and patient eligibility

About

With ongoing war in Iraq, the incidence of posttraumatic stress disorder (PTSD) in combat veterans is increasing. Creation, implementation, and testing of new and innovative interventions are needed to provide additional options for enhancing the mental health of those with PTSD. Surveys indicate that veterans are interested in complementary approaches to health care. The purpose of this study is to determine the efficacy of the Mantram Repetition Program (MRP) delivered as a brief, 6-week, complementary and portable intervention. It includes frequent, silent repetitions of a mantram (mantra), a word or phrase with spiritual associations, to manage PTSD symptoms and improve quality of life military veterans with trauma.

Full description

The Mantram Repetition Program (MRP) is an innovative, portable meditation-based group intervention. In this study, the MRP was delivered in addition to usual care (defined as case management and medication) in a 6-week (90 minutes/week) group setting. The MRP was compared to usual care only.

This 4-year study employed a mixed-methods, prospective, randomized controlled trial with qualitative phone interviews at 3 months post-intervention to explore ways that the intervention was used. Outpatient Veterans (N=146) with military-related PTSD were recruited from a single VA site and randomly assigned to the experimental arm (n=71) which consisted of usual care and the mantram program versus usual care only control group (n=76).

Enrollment: 146 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary diagnosis of PTSD, military related
• Score of greater or equal to 45 on the Clinician Administered PTSD Scale
• Read and write English
• Score of > 50 on PTSD Checklist
• Has a telephone with answering machine or voice mail to receive study messages
• Has a Case Manager assigned for usual care
• Willingness to track medications, relaxation techniques and number of case manager visit

Exclusion criteria

• Cognitive impairment including active psychosis, untreated bipolar disorder, dementia or personality disorder that interferes with group participation
• Presence of active, serious suicidal ideation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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146 participants in 2 patient groups

Arm 1: Mantram + Usual Care

Experimental group

Description:

Mantram Repetition Program for PTSD delivered in this study as 6-week, 90-minute per week that targeted PTSD symptoms. It was offered as an adjunct to usual care consisting of medication and case-management.

Treatment:

Other: Usual care consisting of medication and case management

Behavioral: Mantram Repetition Program (MRP) plus Usual Care

Arm 2: Usual Care alone

Active Comparator group

Description:

Usual care alone is defined as receiving 6 weeks of medication and case management, as needed by each patient. No group meetings.

Treatment:

Other: Usual care consisting of medication and case management