ClinicalTrials.Veeva

Menu

Manual Lymphatic Drainage for Rheumatoid Arthritis

S

Selcuk University

Status

Completed

Conditions

Effect of Manual Lymphatic Drainage on Upper Extremity Functionality in Rheumatoid Arthritis

Treatments

Other: manual lymphatic drainage
Other: excersize

Study type

Interventional

Funder types

Other

Identifiers

NCT05529537
2022/08-01

Details and patient eligibility

About

Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disease characterized by inflammation of the synovial joints and tendon sheaths. As a result of synovitis, progressive damage occurs in cartilage, bone and joints. This damage leads to severe functional limitations and deterioration in quality of life. Synovial tissues are the main site of involvement. Manual lymph drainage reduces the levels of inflammatory mediators associated with edema and pain in the acute phase. On the basis of this concept; Stimulating the lymph system and increasing circulation, removing biochemical residues, regulating sympathetic and parasympathetic system responses, and thus reducing edema and pain. The increase in cardiac parasympathetic activity measured after MLD also contributes to relaxation. In addition to the transport of lymphatic fluid, manual lymph drainage stimulates free nerve endings in the skin with the touches it contains. Gentle stimulation to the skin increases tactile input and closes the pain pathways. In addition, the superficial relaxation and warming provided by soft stimulation creates an effect on the autonomic nervous system and activates the parasympathetic system. The aim of this study is to evaluate the effect of manual lymphatic drainage on upper extremity functionality in individuals with rheumatoid arthritis.

Enrollment

39 patients

Sex

Female

Ages

25 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Diagnosed with RA according to ACR criteria
  • Being between the ages of 18-65
  • Volunteering to participate in the study

Exclusion criteria

  • Presence of neuromuscular disease
  • Having difficulty walking
  • Cognitive impairment
  • Having systemic disease such as diabetes mellitus and osteoarthritis
  • History of upper extremity sIf you have Hand Deformity

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

39 participants in 2 patient groups

control
Active Comparator group
Treatment:
Other: excersize
MLD
Experimental group
Treatment:
Other: excersize
Other: manual lymphatic drainage

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems