Manual Therapy Effects on Upper and Lower Esophageal Sphincter Pressures

University Hospital, Motol

Status: Completed

Conditions: Globus Pharyngeus; Gastroesophageal Reflux Disease

Treatments: Procedure: manual therapy

Study type: Observational

Funder types: Other

Identifiers

NCT03871426

GERD2_2019

Details and patient eligibility

About

The aim of this study is to test the influence of manual cervical traction and chest stabilization maneuvers on pressures in upper and lower esophageal sphincters.

Full description

High Resolution Manometry (HRM) will be used to measure pressure changes in upper esophageal sphincter (UES) and lower esophageal sphincter (LES) during manual cervical traction and trunk stabilization maneuvers. 50-55 gastroesophageal reflux disease (GERD) subjects will participate in the study. UES and pressures will first be measured in relaxed supine position then, during manual cervical traction and finally, the subjects will undergo manual positioning of the trunk into neutral position and LES and UES pressures will be measured again.

Enrollment: 54 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Gastroesophageal reflux disease

Exclusion criteria

• Previous gastro- esophageal surgery
• Concomitant other chronic disease that would affect esophageal motility
• Esophageal structural pathology
• Massive hiatus hernia