Manual Therapy in Haemophilic Arthropathy of the Knee (ARTHROPA)

Universidad Católica San Antonio de Murcia

Status: Completed

Conditions: Patients With Haemophilia

Treatments: Other: Educational Physiotherapy; Other: Manual Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT02198014

ARTHROPAT

ARTHROPATHY

Details and patient eligibility

About

This study aims to assess the effectiveness of two Physiotherapy treatments: one with manual therapy using joint traction, passive muscle stretching, and isometric exercise, active resisted and proprioception exercises; and other treatment with educational sessions and home exercises to improve the ROM, muscle strength and proprioception in patients with haemophilia and arthropathy of the knee.

Full description

Randomized trial with two treatment groups: one using joint traction, passive muscle stretching and isometric exercises, active resisted and proprioception exercises (group MT); and another with educational sessions and home exercises (group E); and a control group (group C).

The intervention was carried out during twelve weeks, performing evaluation before and after treatment, and six months of finalizing this. The treatment in MT group consisted of two sessions per week for one hour each, and the treatment in group E consisted of a session of 90 minute every two weeks, with exercises daily home. The control group (group C) did not receive any treatment. After the allocation to the groups, the composition was follows: MT group = 7; E group = 7; and control group = 7.

Enrollment: 21 patients

Sex: Male

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients must be over the age of 18 years
• Diagnosis of haemophilia A or B
• Patients with haemophilic arthropathy in one or both knees

Exclusion criteria

• Patients who had a haemarthrosis of knee during intervention
• Patients with different medical diagnosis (eg, Von Willebrand's disease)
• Patients with antibodies to FVIII or FIX (inhibitors).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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21 participants in 3 patient groups

Manual Therapy group

Experimental group

Description:

We employed joint traction, passive muscle stretching and isometric exercises, active resisted and proprioception exercises. The treatment in this group consisted of two sessions per week for one hour each.

Treatment:

Other: Manual Therapy

Educational gruop

Experimental group

Description:

This group received educational sessions and home exercises. The exercises are aimed at improving quadriceps strength, flexibility, range of motion and knee proprioception. Each educational session of 90 minute every two weeks, with exercises daily home

Treatment:

Other: Educational Physiotherapy

Control group

No Intervention group

Description:

The control group (group C) did not receive any treatment. The patients of this group were assessed by the same reviewers and under the same conditions as the subjects of the two intervention groups.