Manual Therapy in Tension-type Headache

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Status: Completed

Conditions: Tension-Type Headache

Treatments: Procedure: manipulation plus exercise; Procedure: suboccipital inhibition plus exercise; Procedure: exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT04546165

2020/289

Details and patient eligibility

About

Tension-type headache (TTH) causes a significant negative impact on working and daily life due to the reduction in work productivity and family and social activities causes. There is evidence that manual therapy and exercise reduce nociceptive input from the cervical spine and surrounding muscles, the use of manual therapy in TTH management

Full description

Increased cranio-cervical muscle sensitivity is the most prominent finding in TTH. Also, neck pain is markedly more common in individuals with TTH compared with the control population (88.4%, and 56.7%, respectively). Therefore, current research on the pathogenesis of TTH focuses on the role of musculoskeletal disorders in the cervical spine and the facilitation of nociceptive pain processing. It has been suggested that peripheral sensitivity of nociceptors in cranio-cervical muscles and other cervical structures, as well as sensitivity of nociceptive pain pathways in the central nervous system (CNS) due to long-term nociceptive stimuli may play a role in development and chronification of TTH

Enrollment: 45 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis of TTH was made based on the International Classification of Headache Disorders criteria, third edition (ICHD-3 beta)
• (bilateral localization, pressing and tightening pain, mild-moderate intensity [≤7.0 on a visual analog scale (VAS)]
• no increase in pain during physical activity
• patients did not report any photophobia, phonophobia, vomiting or nausea, as requested by the ICHD-III diagnostic criteria
• had symptoms for more than 3 months
• the patients had to have had at least one segmental dysfunction of the upper cervical spine in all groups (by functional and pain-provocation tests).

Exclusion criteria

• any other primary or secondary headache according to the ICHD-III criteria
• a history of neck or head trauma (e.g., whiplash)
• any red flags (vertebral tumor, fracture, dislocation and infection, metabolic diseases, rheumatic and connective tissue diseases, systemic neuromuscular diseases, prolonged history of steroid use)
• diagnosis of any structural spinal disorders (osteoporosis, disc herniation, myelopathy, spinal stenosis, spondylolisthesis)
• prior surgery to the cervical spine
• application of other treatment methods such as physical therapy or anesthetic block to the head and neck area within the last 3 months
• initiation of pharmacologic prophylaxis within two months prior to randomization
• pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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45 participants in 3 patient groups

manipulation group

Active Comparator group

Description:

manipulation plus exercise

Treatment:

Procedure: suboccipital inhibition plus exercise

Procedure: exercise

myofascial release group

Active Comparator group

Description:

suboccipital inhibition plus exercise

Treatment:

Procedure: exercise

Procedure: manipulation plus exercise

exercise group

Active Comparator group

Description:

only exercise

Treatment:

Procedure: suboccipital inhibition plus exercise

Procedure: manipulation plus exercise