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Mapping Aspects of Psychotherapy in Dialectical Behavior Therapy (MAP-DBT)

University of Massachusetts, Amherst logo

University of Massachusetts, Amherst

Status

Completed

Conditions

Borderline Personality Disorder

Treatments

Behavioral: Dialectical behavior therapy - emotion regulation skills training
Behavioral: Interpersonal psychotherapy
Behavioral: Dialectical behavior therapy - interpersonal effectiveness skills training

Study type

Interventional

Funder types

Other
NIH

Identifiers

NCT04626310
R21MH119530-01A1 (U.S. NIH Grant/Contract)
1710 1R21MH119530-01A1

Details and patient eligibility

About

Although dialectical behavior therapy (DBT) skills training is effective in the treatment of borderline personality disorder, it contains four skills modules and there is little research to guide their modular application. This study compares the unique effects of two distinct DBT skills training modules, relative to a non-DBT therapy group for adults with borderline personality disorder. Using innovative laboratory-based assessment methods, the proposed study will examine the effects of these conditions on emotional responding and interpersonal functioning, as well as clinical outcomes.

Full description

Borderline personality disorder (BPD) is a severe mental health condition with high morbidity and mortality. Although dialectical behavior therapy (DBT) is an efficacious treatment for BPD, it is resource-intensive and lengthy in its full form, involving one year of weekly individual therapy and group skills training in mindfulness, emotion regulation, interpersonal effectiveness, and distress tolerance. As a result, few patients have access to the full treatment. A better understanding of how the distinct components of DBT affect different sets of symptoms could help to streamline this treatment and personalize its use with specific patients.

Improvements in both interpersonal and emotional functioning are theorized to underlie improvements in BPD. Thus, emotion regulation and interpersonal effectiveness skills training may be particularly important components of DBT. Therefore, this study examines the unique effects of two distinct DBT skills training modules.

Participants are adults with BPD and recent, recurrent self-injurious behaviors (planned N = 81) who are randomly assigned to six weeks of DBT emotion regulation skills training (DBT-ER), DBT interpersonal effectiveness skills training (DBT-IE), or a non-skills control group. Using innovative laboratory-based multimethod assessments, this study examines the effects of these conditions on emotional responding and interpersonal functioning, as well as BPD related outcomes. Aim 1 examines the unique effects of DBT-ER and DBT-IE on their respective emotion-related (subjective and biological emotional reactivity, behavioral emotion regulation, skills use) and interpersonal (subjective and behavioral) targets, compared to the non-DBT treatment. Aim 2 examines whether improved emotional functioning predicts reductions in BPD symptoms and self-injury. Aim 3 examines whether baseline emotion dysregulation interacts with treatment condition to predict treatment response.

The proposed research is innovative in its experimental examination of the effects of DBT components on specific targets in BPD. Given the high societal costs of BPD, this work has important public health significance. Findings will inform larger studies evaluating the potential modular use of DBT components to result in briefer and more efficient individualized treatments for patients.

Enrollment

84 patients

Sex

All

Ages

18 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. exhibit 4+ BPD symptoms,
  2. have a history of recent (i.e., past-year) and recurrent (> 1 instance) of self-injury,
  3. commit to participate in one of our 6-week experimental groups,
  4. have an individual health provider who can manage imminent issues,
  5. be between 18-60 years old,

Exclusion criteria

  1. not fluent in English,
  2. have impaired (uncorrected) vision or hearing that would impair ability to understand study stimuli,
  3. a current manic, psychotic, or active physiological dependence on substances (to limit interference in the lab),
  4. low cognitive functioning (IQ ≤ 70.4 (TOPF; Pearson Assessments, 2009),
  5. past DBT treatment

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

84 participants in 3 patient groups

Dialectical behavior therapy - emotion regulation skills training
Experimental group
Description:
Dialectical behavior therapy - emotion regulation skills training
Treatment:
Behavioral: Dialectical behavior therapy - emotion regulation skills training
Dialectical behavior therapy - interpersonal effectiveness skills training
Experimental group
Description:
Dialectical behavior therapy - interpersonal effectiveness skills training
Treatment:
Behavioral: Dialectical behavior therapy - interpersonal effectiveness skills training
Non-skills-oriented interpersonal psychotherapy group
Active Comparator group
Description:
Non-skills-oriented interpersonal psychotherapy group
Treatment:
Behavioral: Interpersonal psychotherapy

Trial documents
1

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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