Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging (S48)

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Purdue University

Status

Completed

Conditions

Flaccid Muscle Tone

Treatments

Procedure: muscle biopsy

Study type

Interventional

Funder types

Other

Identifiers

NCT02685319
1512016862

Details and patient eligibility

About

Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging

Full description

The aim of this study is to obtain human muscle samples for cell culturing to analyze muscle cell development in real-time to uncover factors that influence growth.

Enrollment

7 patients

Sex

Male

Ages

20 to 29 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

-Inclusion Criteria:

  • men 20-29 yrs
  • BMI between 20 and 34.9
  • Fasting Glucose <110 mg/dL
  • Blood Pressure <160/100mm Hg
  • Non-Diabetic
  • LDL-Cholesterol <160mg/dL
  • Triacylglycerol <400 mg/dL
  • Makers of kidney, liver, and heart functions within 10% of clinical normalcy
  • <1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months

Exclusion Criteria:

  • men <20or>29 yrs

    • BMI between <20 and >34.9

    • Fasting Glucose >110 mg/dL

    • Blood Pressure >160/100mm Hg

    • Non-Diabetic

    • LDL-Cholesterol >160mg/dL

    • Triacylglycerol >400 mg/dL

    • Pre-existing kidney or liver conditions

      -->1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months

    • Currently taking prescribed blood thinners

Trial design

Primary purpose

Other

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

7 participants in 1 patient group

muscle biopsy
Experimental group
Description:
a muscle sample will be taken from the mid-thigh (Vastus Lateralis) and analyzed
Treatment:
Procedure: muscle biopsy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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