Marginal Periosteal Pedicle Flap - Platelet Rich Fibrin Barriers in Treating Periodontal Intrabony Defects

Al-Azhar University

Status and phase: Completed; Phase 2

Conditions: Periodontal Pocket

Treatments: Procedure: Regenerative therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT02359539

Ain Shams University

Details and patient eligibility

About

The use of autogenous graft materials has been recorded to be a gold standard in regenerative therapy. This study directed toward evaluation of two autogenous regenerative materials, marginal periosteal pedicle graft (MPP) and platelet rich fibrin (PRF) as membrane barriers for treating intrabony defects. In spite of its reported significant clinical outcomes, the limited availability of the periosteum makes it necessary to evaluate other autogenous alternatives such as PRF that could offer predictable outcomes.

Full description

Material and methods: 10 patients with sever chronic periodontitis and at least single ≥4 mm intrabony defect had participated in this randomized clinical study. Subjects were randomly divided into2 groups, Group 1(MPP) defect coverage with xenograft defect fill(10 patients),Group 2(PRF) defect coverage with xenograft defect fill(10 patients).Clinical and radiographic measurements were carried out at 3,6 and 9 months postoperatively.

Enrollment: 10 patients

Sex: All

Ages: 20 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• No systemic diseases that could influence the outcome of therapy
• Good compliance for plaque control instructions after initial therapy
• Vital teeth
• Had contralateral matched pair of 2- or 3-walled intrabony interproximal defects in premolar or molar teeth
• Probing pocket depth (PPD)≥6 mm and clinical attachment level (CAL) ≥4mm 6) selected 2- or 3-wall intrabony defect depth ≥ 3 mm as detected in diagnostic periapical radiographs,

Exclusion criteria

• Pregnant females and patients presented with opened interproximal contact

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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10 participants in 2 patient groups

PRF

Experimental group

Description:

Platelets rich fibrin,

Treatment:

Procedure: Regenerative therapy

MPP

Experimental group

Description:

Marginal periosteal pedicle

Treatment:

Procedure: Regenerative therapy