Markers and Calculation of Cardiovascular Risk in the Distinct Phenotypes of Polycystic Ovary Syndrome

Aristotle University Of Thessaloniki

Status: Unknown

Conditions: Polycystic Ovary Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT01392781

14/1-3-2011

Details and patient eligibility

About

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder and cause of anovulatory infertility among reproductive aged women. According to the revised criteria of 2003, four distinct phenotypes of PCOS can be diagnosed. However, there are emerging evidence supporting the existence of different levels of cardiometabolic risk between the four phenotypic groups of the syndrome. The purpose of this study is to determine the cardiovascular risk of i) normoweight and ii)overweight plus obese women of every one of the four phenotypes of the syndrome as well as the levels of low inflammation serum markers and the possible correlations of the between the outcomes.

Enrollment: 300 estimated patients

Sex: Female

Ages: 15 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diagnosis of PCOS (criteria 2003)
• Healthy controls

Exclusion criteria

• any condition mimicking PCOS
• any systematic disease

Trial design

300 participants in 4 patient groups

normoweight PCOS patients

normoweight controls

overweight plus obese PCOS patients

overwqeight plus obese controls