Markers of Prognosis and Response to Therapy in Patients With Metastatic Brain Tumors Undergoing Stereotactic Radiosurgery (SRS)

Swedish Medical Center

Status: Unknown

Conditions: Metastatic Brain Tumor

Study type: Observational

Funder types: Other

Identifiers

NCT01908179

SRS - Mets

Details and patient eligibility

About

This registry study will evaluate patients with metastatic brain tumors undergoing, or having undergone, stereotactic radiosurgery (SRS) at Swedish Medical Center. Clinical outcomes will be evaluated at the 3, 6 and 12-month time points. Clinical data, SRS treatment data, and imaging data (including anatomic and advanced imaging sequences obtained prior to and serially following SRS) will be archived in an online informatics platform, specifically a metastatic brain tumor registry known as the Comprehensive Neuro-oncology Data Repository for Metastatic Tumors (CONDR - Mets).

Enrollment: 100 estimated patients

Sex: All

Ages: 19 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients (>18 yo) with a pathological diagnosis of metastatic brain cancer
• Participants must have >4 tumors felt to require stereotactic radiosurgery
• Karnofsky scale of > 70 at the time of initial treatment
• Age < 80

Exclusion criteria

• Karnofsky scale <70
• Age > 80
• Inability to undergo MR imaging studies