Massive Nasal Bleeding in Patients With NPC Received Curative RT

Taichung Veterans General Hospital

Status: Completed

Conditions: Nasopharyngeal Carcinoma Patients Treated With Curative Radiotherapy

Treatments: Other: Patients with massive nasal bleeding; Other: Patients without massive nasal bleeding

Study type: Observational

Funder types: Other

Identifiers

NCT06348485

VGHTCCTC_NPCbleeding001

Details and patient eligibility

About

To investigate the incidence, predictive markers, and survival impact of massive nasal bleeding in nasopharyngeal carcinoma (NPC) patients who received curative radiotherapy (RT) with/without chemotherapy. A total of 1327 patients with previously untreated, biopsy-proven NPC, and no distant metastasis were retrospective reviewed. Investigators analyzed the occurrence rates of massive nasal bleeding between different characteristics and tried to identify important predictive factors. Investigators compared overall survival between patients with and without massive nasal bleeding by Kaplan-Meier method.

Enrollment: 1,327 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• previously untreated, biopsy-proven NPC
• no distant metastasis

Exclusion criteria

• incomplete record of history or treatment

Trial design

1,327 participants in 1 patient group

NPC received Curative radiotherapy

Treatment:

Other: Patients without massive nasal bleeding

Other: Patients with massive nasal bleeding