Maternal and Infant Cord Blood Monosaccharide Content

Arkansas Children's Hospital Research Institute

Status: Completed

Conditions: Pregnancy

Study type: Observational

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT00783770

31247

Details and patient eligibility

About

Mother's breast milk provides many benefits to babies with regard to development and improved health. We believe the simple sugars which make up these complex sugars in breast milk and are also found in the brain may be critical to normal brain development in term and preterm infants.

Babies are exposed to these sugars by placental transport during pregnancy and through mother's breast milk after they are born. For the preterm infant, we do not know if breast milk gives enough of these sugars compared to what the baby gets during pregnancy.

A maternal blood sample and blood samples from the baby's umbilical cord will provide us with background information for developing a supplement of special sugars that can be added to infant formulas to provide the amount that the baby usually gets during pregnancy and from breast milk.

Enrollment: 48 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Healthy mothers with ages ranging from 18 to 35 yrs
• Delivered infants appropriate weight for gestational age (between 10% and 90%)

Exclusion criteria

• Maternal history of smoking, alcohol or drug use

Trial design

48 participants in 3 patient groups

30-33 weeks

Description:

mother infant pairs with gestation of 30-33 weeks

34-37 weeks

Description:

mother infant pairs with gestation of 34-37 weeks

38-42 weeks

Description:

mother infant pairs with gestation of 38-42 weeks