Maternal Body Composition Regulates Placental Function (MBC)

National Center for Research Resources (NCRR)

Status: Completed

Conditions: Obesity; Pregnancy

Treatments: Other: No intervention

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT02586714

2KL2RR024141-06

Details and patient eligibility

About

This study examined the relationships between maternal body composition, placental function, and fetal nutrition and body composition, and sought to determine the most accurate method of maternal body composition analysis in late pregnancy.

Full description

This study examined the relationships between maternal body composition, placental function, and fetal nutrition and body composition, and sought to determine the most accurate method of maternal body composition analysis in late pregnancy. This project integrates body composition analysis, nutrition, and metabolic factors to study the impact of maternal body composition and diet on placental function and fetal growth.

Research Project: The proposed enrollment of 41 pregnant women at term (>37 weeks gestation) was completed in September 2013. The subjects underwent four body composition measurements (bioelectrical impedance, skin-fold thickness, BodPod, and deuterium dilution) and dietary surveys along with a fasting blood draw. The subjects returned 2 weeks postpartum for repeat measurements along with a DEXA scan.

Enrollment: 41 patients

Sex: Female

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Healthy pregnant women at term with singleton gestation

Exclusion criteria

Medical condition requiring daily medication Fetal congenital anomalies Diabetes

Trial design

41 participants in 3 patient groups

Normal weight

Treatment:

Other: No intervention

Overweight

Treatment:

Other: No intervention

Obese

Treatment:

Other: No intervention