Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms (MOMS-AD)

University of Illinois

Status: Not yet enrolling

Conditions: Alcohol Use; Contingency Management; Postpartum Depression (PPD); Problem Solving Therapy

Treatments: Behavioral: Contingency Management & Problem Solving Therapy; Other: Usual Care

Study type: Interventional

Funder types: Other

Identifiers

NCT07485036

2026-0112

Details and patient eligibility

About

This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms. The main questions it seeks to answer are:

1. How do new mothers fare with depressive symptoms and alcohol use in the first 12 months after giving birth?
2. Will a CM-PST intervention reduce depressive symptoms and alcohol use frequency among new mothers?
3. Is a CM-PST intervention practical for new mothers?

The researchers will recruit approximately 30 new mothers and randomly select half to attend a 6-week CM-PST intervention. They will compare those who received the intervention versus those who did not to see if there are any differences in their depressive symptoms and alcohol usage.

Participants will:

• Complete 4 remote intervention sessions over 6 weeks
• Conduct at-home urine drug tests 2x per week during the 6-week intervention
• Answer online surveys about their mental health and alcohol use

Enrollment: 30 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Biologically female
• Age ≥18 years
• Within 12 months postpartum
• Able to provide informed consent

Exclusion criteria

• Serious medical or psychiatric conditions requiring hospitalization
• Lifetime DSM-5 diagnosis of schizophrenia, bipolar disorder, or any psychiatric disorder
• Current use of psychoactive drugs, medication to treat problematic alcohol use, or depression
• Participation in past 6 months in problematic alcohol use or substance use treatment
• Unable to provide consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups, including a placebo group

Contingency Management & Problem Solving Therapy (CM-PST) Intervention Group

Experimental group

Description:

Receives 4 remote sessions of CM-PST therapy over 6 weeks while conducting at home urine drug tests 2x weekly.

Treatment:

Behavioral: Contingency Management & Problem Solving Therapy

Usual Care Control Group

Placebo Comparator group

Treatment:

Other: Usual Care