Maternal Polyunsaturated Fatty Acids in Association With Child Autism Spectrum Disorder in the MARBLES Study

University of California (UC) Davis

Status: Completed

Conditions: Autism Spectrum Disorder

Treatments: Behavioral: Maternal Supplemental PUFA Intake

Study type: Observational

Funder types: Other

Identifiers

NCT03468959

225645

Details and patient eligibility

About

This study is to examine the association between maternal omega3 and other polyunsaturated fatty acids (PUFAs) during pregnancy and autism spectrum disorder (ASD) as well as other non-typical development (Non-TD) in the prospective Markers of Autism Risk in Babies-Learning Early Signs (MARBLES) cohort.

Enrollment: 252 patients

Sex: All

Ages: 3+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Mother or father had a biological child with ASD
• Mother is at least 18 years old
• Mother is pregnant or planning a pregnancy, and biologically able to become pregnant
• Mother is living within 2 hours of the MIND Institute
• Mother is sufficiently fluent in English

Exclusion criteria

• Mothers with diseases which will influence on their study participation

Trial design

252 participants in 1 patient group

Mother-child pairs

Description:

Families were recruited from lists of children receiving autism services obtained via the California Department of Developmental Services (DDS), from other studies at the Medical Investigation of Neurodevelopmental Disorders (MIND) Institute, or by self-referrals. The inclusion criteria were: a) mother or father had a biological child with ASD, and the mother was b) at least 18 years old; c) pregnant or planning a pregnancy, and biologically able to become pregnant; d) living within 2 hours of the MIND Institute; e) sufficiently fluent in English.

Treatment:

Behavioral: Maternal Supplemental PUFA Intake