Maternal Psychopathology and Offspring Mental Health (PSI_PER)

University of Milano Bicocca

Status: Completed

Conditions: Intergenerational Relations

Study type: Observational

Funder types: Other

Identifiers

NCT03897816

981

Details and patient eligibility

About

Pregnant women consecutively referred to the Perinatal Psychiatric Outpatient Department, those in charge of the Psychiatric Outpatient Department and pregnant healthy controls from the general population will be recruited on a voluntary basis. Mothers will be tested with the EPDS, BAI, BDI, WHOQOL, SCID II and CTQ; their children will be tested with the CBCL between 18 months and 5 years.

Full description

in order to attest possible psychic outcomes in offspring of mothers affected by psychiatric disorders due to maternal psychopathology (with an in-depth evaluation about the role of maternal personality disorders), the investigators recruit all the women consecutively referred and admitted to the Perinatal Psychiatric Outpatient Department from January, 2011 to December, 2016, due to the manifestation of psychic suffering during pregnancy.

During their first appointment, patients are routinely administered the Structured Clinical Interview for DSM-IV Axis II Disorders (SCID II), Childhood Trauma Questionnaire (CTQ), World Health Organization Quality of Life Instruments (WHOQOL-BREF), Edinburgh Postnatal Depression Scale (EPDS), Beck Depression Interview (BDI) and Beck Anxiety Interview (BAI). The Mini-International Neuropsychiatric Interview (M.I.N.I.) is used to confirm clinical diagnosis.

As a control samples, the investigators recruited pregnant patients belonging to the Outpatients Psychiatric Department who did not have psychiatric issues linked to their pregnancy or in the relationship with their children and pregnant healthy controls among the general population, with no history of mental health issues. Controls were tested as the clinical sample.

All the patients will be asked to complete a caregiver report form, the Child Behavior Checklist (CBCL), once their children were at least 18 months old.

Enrollment: 450 patients

Sex: Female

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

pregnancy; adequate comprehension; acceptance on a voluntary basis.

Exclusion criteria

incapacity; acute psychosis.

Trial design

450 participants in 3 patient groups

"PERINATAL"

Description:

Pregnant women consecutively referred and admitted to the Perinatal Psychiatric Outpatient Department

"OUTPTS"

Description:

Pregnant women belonging to the Outpatients Psychiatric Department who did not have psychiatric issues linked to their pregnancy or in the relationship with their children

Healthy controls

Description:

Pregnant women the general population, with no history of mental health issues