Maternal Serum Homocysteine Levels and Uterine Artery Pulsatility Indices in Preterm Labor

Benha University

Status: Completed

Conditions: Preterm Labor

Treatments: Diagnostic Test: Uterine artery doppler; Diagnostic Test: Maternal serum homocysteine estimation

Study type: Observational

Funder types: Other

Identifiers

NCT03440281

1182015

Details and patient eligibility

About

Study included all pregnant women admitted with threatened preterm labor during the study period. All participants underwent estimation of maternal serum homocysteine level and assessment of uterine artery Doppler indices.

Full description

Prospective cohort study. Study approval by local ethics committee. Informed written consent. Study included all pregnant women admitted with threatened preterm labor during the study period. All participants underwent estimation of maternal serum homocysteine level and assessment of uterine artery Doppler indices.

Enrollment: 200 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Singleton pregnancy
• More than 28 and less than 35 gestational weeks.
• Threatened preterm labor

Exclusion criteria

• Medical disorders complicating pregnancy
• Obstetric conditions complicating pregnancy (e.g., placenta previa, multiple gestation,PPROM, ....etc)
• Fetal anomalies or distress

Trial design

200 participants in 2 patient groups

Preterm group

Description:

included pregnant females delivered prior to completed 37 weeks of gestation. All participants underwent assessment of uterine artery Doppler indices and maternal serum homocysteine estimation

Treatment:

Diagnostic Test: Maternal serum homocysteine estimation

Diagnostic Test: Uterine artery doppler

Term group

Description:

Included pregnant females delivered after completed 37 weeks of gestation. All participants underwent assessment of uterine artery Doppler indices and maternal serum homocysteine estimation

Treatment:

Diagnostic Test: Maternal serum homocysteine estimation

Diagnostic Test: Uterine artery doppler