Matrix Metalloproteinase (MMP) in Heart Failure

Tottori University Hospital

Status: Completed

Conditions: Chronic Stable Heart Failure

Study type: Observational

Funder types: Other

Identifiers

NCT00663494

#244

Details and patient eligibility

About

The purpose of this study is to evaluate the production of MMP in failing hearts.

Full description

Myocardial fibrosis is observed in failing hearts and parallel to the progression of chronic heart failure (CHF) and myocardial remodeling. Matrix metalloproteinases (MMPs) are considered markers of fibrosis. Recently, circulating MMPs can be measured and are elevated in patients with CHF. However, MMPs it is still unclear whether MMPs are produced in failing hearts. Thus, the purpose of this study is to evaluate the production of MMP in failing hearts.

Enrollment: 22 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• chronic stable heart failure