Matrix Metalloproteinases in Atherosclerosis of Chronic Kidney Disease (MMACKD)

Aristotle University Of Thessaloniki

Status: Unknown

Conditions: Diabetic Nephropathy

Study type: Observational

Funder types: Other

Identifiers

NCT01458158

A13749

31-8-2010 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to determine whether matrix metalloproteinases are associated with atherosclerosis in the different stages of chronic kidney disease.

Full description

The purpose of this study is to determine the correlation of matrix metalloproteinases and atherosclerosis of chronic kidney disease. Patients with diabetes mellitus type 2,as a non-inflammatory leading cause of end stage renal failure and patients with chronic glomerulonephritis and similar course of proteinuria,as an inflammatory leading cause of end stage renal failure are enrolled.

Enrollment: 300 estimated patients

Sex: All

Ages: 50 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Chronic kidney disease
• Diabetes mellitus type 2

Exclusion criteria

• Malignancy

Trial design

300 participants in 3 patient groups

Diabetic nephropathy

Description:

Diabetic nephropathy in patients with type 2 diabetes

chronic glomerulonephritis

Description:

chronic glomerulonephritis in patients without diabetes mellitus

controls

Description:

participants without diabetic nephropathy and chronic glomerulonephritis