Maxillary and Mandibular Nerve Block (nerve block)

Mansoura University

Status: Enrolling

Conditions: Analgesia

Treatments: Procedure: Maxillary and mandibular nerve block; Other: Control

Study type: Interventional

Funder types: Other

Identifiers

NCT05925465

Jaw nerve block

Details and patient eligibility

About

Mandibular fractures are among the most common (60-70%) maxillofacial fractures observed in emergency rooms. In the closed reduction (non-surgical), the bone fragments are realigned manually or by using traction devices. The open reduction surgery of mandibular fractures should first ensure the restoration of the occlusion of the mandible to prevent postoperative malocclusion, followed by stabilization by means of rigid fixations such as plates, screws, and rigid intermaxillary blocks in order to minimise any nonunion, malunion, or delayed union of the fracture segments. These surgical procedures are associated with moderate postoperative pain, being the first 24 hours the most intense pain period. Maxillary and mandibular nerve blocks are performed in patients with refractory trigeminal neuralgia. However, there have been few studies evaluating the analgesic effects of these blocks for maxillofacial surgeries.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists (ASA) I/II patients,
• within the age group of 21-60 years
• both sex
• scheduled for elective faciomaxillary surgery

Exclusion criteria

• Pregnant or breast-feeding women
• Patients with polytrauma
• Patients necessitating postoperative ventilation
• Oral or facial infection
• Coagulopathy
• Drug intake for chronic pain
• Known allergy to the study drugs
• Psychiatric disorder

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups, including a placebo group

Maxillary and mandibular nerve block (MMNB) group

Active Comparator group

Description:

receive bilateral combined maxillary and mandibular nerve block. Three mL of 0.5% isobaric bupivacaine will be injected for each nerve block after negative aspiration of blood.

Treatment:

Procedure: Maxillary and mandibular nerve block

Control (C) group

Placebo Comparator group

Description:

not receive any nerve block

Treatment:

Other: Control