Maxillary Sinus Grafting With Deproteinized Porcine or Bovine Bone Mineral.

Camlog Oral Reconstruction Foundation

Status: Completed

Conditions: Histomorphometry

Treatments: Procedure: Maxillary sinus augmentation

Study type: Interventional

Funder types: Other

Identifiers

NCT05804253

CamlogORF

Details and patient eligibility

About

The present study aimed to compare the histomorphometrically evaluated new bone formation, the radiographically measured graft stability and the clinical implant outcome between maxillary sinuses grafted either with deproteinized porcine bone mineral (DPBM) or deproteinized bovine bone mineral (DBBM). Conclusions: From a clinical point of view, the present results demonstrate that DPBM provides for comparable bone formation and stable graft dimension and high implant success rates combined with healthy peri-implant condition:

Full description

Materials and Methods: Thirty maxillary sinuses in 28 participants were initially included and randomly assigned to the test group (TG;DPBM: n=15) or the control group (CG,DBBM: n=15). After a healing period (6 months) bone core biopsies were axially retrieved in the molar site for histological/ histomorphometrical analysis of new bone formations. In addition, radiographically measured graft stability as well as the clinical implant outcome (implant survival/success/peri-implant health) were assessed at the 1-year and 3-year follow-up evaluations.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• maxillary sinus atrophy in the need of sinus augmentation, 2 stage augmentation procedure

Exclusion criteria

• drug abuse, additional augmentation procedure, heavy smokers, bisphosphonate abuse

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

bovine bone

Active Comparator group

Description:

Patients received maxillary sinus augmentation grafting with bovine bone mineral

Treatment:

Procedure: Maxillary sinus augmentation

Porcine bone mineral

Active Comparator group

Description:

patients received maxillary sinus augmentation grafting with porcine bone mineral

Treatment:

Procedure: Maxillary sinus augmentation