Mayo Clinic Precure - Prospective Study

Mayo Clinic

Status: Enrolling

Conditions: Genetic Predisposition; Exposure, Environmental

Study type: Observational

Funder types: Other

Identifiers

NCT07332598

25-005869

Details and patient eligibility

About

The goal of this observational study is to 1) better understand and predict biological processes before disease begins or is identified, 2) study genomic and environmental contributors to disease, 3) identify ways to stop disease advancement before it becomes serious or complex, and 4) identify potential targets for disease therapy.

Participants will be asked to:

• collect biological samples,
• download a mobile app,
• collect speech (voice) recordings, and
• complete surveys

Enrollment: 100,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Registered Mayo Clinic patient
• Able to provide informed written consent
• Able to receive mail and packages within a United States (US) state
• Able to collect and ship samples within a US state via FedEx for overnight delivery

Exclusion criteria

• Active hematological cancer or history of a hematological cancer
• Allogeneic Bone Marrow Transplant (autologous bone marrow transplant recipients are acceptable if collected at least one month after transplant)
• Other co-morbidity that, in physician's opinion, would interfere with patient's ability to participate in the study (e.g., reduced ability to comprehend, i.e., dementia, intellectual disability, etc.)

Trial design

100,000 participants in 2 patient groups

Suspected Genetic Predisposition or Multi-Omics Contribution

Description:

Patients with a diagnosis or phenotype with the potential for association with a genetic predisposition or Multi-Omics Contribution

Health Control

Description:

Patients with no diagnosis associated with a genetic predisposition or Multi-Omics Contribution.