Mayo Clinic Tapestry 2.0: Applying Multi-Omics for Scientific Discovery

Mayo Clinic

Status: Invitation-only

Conditions: Genetic Predisposition; Exposure, Environmental

Study type: Observational

Funder types: Other

Identifiers

NCT06456320

23-004120

Details and patient eligibility

About

The purpose of this study is to use multi-omics testing on samples collected from Mayo Clinic patients to build and expand on what has been learned about genomic data.

Enrollment: 10,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Registered Mayo Clinic patient
• Able to provide informed written consent
• Able to receive mail and packages within a United States (US) state
• Able to collect and ship samples within a US state

Exclusion criteria

• Active hematological cancer or history of a hematological cancer
• Allogeneic Bone Marrow Transplant (e.g., samples from autologous bone marrow transplant recipients are acceptable if collected at least one month after transplant)
• Other co-morbidity that, in physician's opinion, would interfere with patient's ability to participate in the study (e.g., reduced ability to comprehend, i.e., dementia, intellectual disability, etc.)

Trial design

10,000 participants in 2 patient groups

Suspected Genetic Predisposition or Multi-Omics Contribution

Description:

Patients with a diagnosis or phenotype with the potential for association with a genetic predisposition or Multi-Omics Contribution.

Healthy Control

Description:

Patients with no diagnosis associated with a genetic predisposition or Multi-Omics Contribution.