MBCT for People With Parkinson's Disease and Caregivers (MBCT-PD-2)

University of California San Francisco (UCSF)

Status: Completed

Conditions: Parkinson Disease; Depression; Anxiety

Treatments: Behavioral: Mindfulness-based cognitive therapy (MBCT)

Study type: Interventional

Funder types: Other

Identifiers

NCT04469049

MZHF_20200962

Details and patient eligibility

About

This study aims to explore the feasibility and effectiveness of mindfulness-based cognitive therapy (MBCT) in reducing anxiety and/or depressive symptoms in people with Parkinson's disease (PD) and caregivers of people with PD.

Full description

An adapted MBCT intervention will be offered to people with Parkinson's disease (PD) and mild-to-moderate depression and/or anxiety, as well as caregivers of people with PD. Several 8-week long MBCT groups will be held between September 2020 and May 2021, based on the adapted protocol. The MBCT intervention will consist of 90-minute weekly groups focused on teaching mindfulness techniques and ways to recognize cognitive patterns that can increase anxiety and/or depression. Participants will be recruited from the community, according to the eligibility criteria detailed below. For all participants, the pre- and post-MBCT anxiety and/or depressive symptom severity and mindfulness levels (as measured with standardized, validated scales) will be compared, using a paired t-test. For caregivers, pre- and post-MBCT caregiver burden scores will be compared as well.

Enrollment: 28 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Having a diagnosis of Parkinson's disease (PD) or parkinsonism, established by a neurologist, or being a caregiver of a person with PD or parkinsonism
• Being able and willing to attend 8 weekly 90-minute online group sessions (5-6:30 pm PST)
• Mild-to-moderate anxiety: GAD-7 score ≤ 16
• Mild-to-moderate depression: PHQ-9 score ≤ 18

Exclusion criteria

• Severe anxiety: GAD-7 score > 16
• Moderately severe-to-severe depression: PHQ-9 score > 18
• Cognitive impairment: Montreal Cognitive Assessment (MoCA) score < 24
• Heavy alcohol or drug use
• Severe psychosis
• Active suicidal or homicidal ideation
• For people with PD: severe motor fluctuations (less than 2 hours "on" time per day)
• Pattern of engagement with health care that indicates low likelihood of completing an 8-week intervention.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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28 participants in 1 patient group

Mindfulness-based cognitive therapy (MBCT)

Experimental group

Description:

All participants will receive the MBCT intervention, consisting of 8 90-minute weekly group sessions.

Treatment:

Behavioral: Mindfulness-based cognitive therapy (MBCT)