MBCT for Psoriasis Patients With Anxiety and Depression

Xi'an Jiaotong University

Status: Unknown

Conditions: Psoriasis

Treatments: Behavioral: mindfulness-based cognitive therapy (MBCT); Other: Antipsoriatic treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT05010044

XJTU1AF-CRF-2019-027

Details and patient eligibility

About

This study investigates the effectiveness of a 24-week mindfulness intervention in reducing symptoms in psoriasis patients with anxiety and depression.

Full description

An adapted MBCT intervention will be offered to people with psoriasis with depression and/or anxiety. 8-week long MBCT therapy will be held between August 2021 and Jan 2022, based on the adapted protocol. The MBCT intervention will consist of 30-minute weekly groups focused on teaching mindfulness techniques and ways to recognize cognitive patterns that can increase anxiety and/or depression. Participants will be recruited from the community, according to the eligibility criteria detailed below. For all participants, anxiety and/or depressive symptom severity(SAS/SDS), PASI,DLQI,(as measured with standardized, validated scales) will be compared baseline and weeks 2;4;8;12;16;20;24. Itch intensity ,itch perception ,quality of sleep, hours missing at work ,helpfulness of common itch therapies serve as the secondary outcome, using a paired t-test.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• the age ranged from 18 to 70 years old
• fulfilled the Classification Criteria for Psoriasis
• the score of the SDS > 50 and / or SAS >50
• Participant has normal or corrected to normal vision and hearing
• Participant is willing and able to give informed consent for participation in the study.

Exclusion criteria

• Participant has insufficient manual dexterity for the computerized tasks
• severe systemic diseases
• patients with severe mental illness or taking psychotic drugs
• Pregnancy
• No access to the internet

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Participants received MBCT once a week for 8 weeks

Experimental group

Description:

Participants received MBCT once a week for 8 weeks. At the same time, the drug therapy for psoriasis was used .

Treatment:

Other: Antipsoriatic treatment

Behavioral: mindfulness-based cognitive therapy (MBCT)

Active comparator

Active Comparator group

Description:

Only the drug therapy for psoriasis was used .

Treatment:

Other: Antipsoriatic treatment