MCG In Long QT Syndrome

Mayo Clinic

Status: Not yet enrolling

Conditions: Atrial Fibrillation

Treatments: Diagnostic Test: Magnetocardiography

Study type: Observational

Funder types: Other

Identifiers

NCT07270211

25-008283

Details and patient eligibility

About

The primary objective of this observational study is to evaluate whether magnetocardiography (MCG) findings more accurately predict clinical outcomes in patients with acquired Long QT syndrome compared to ECG. The secondary objective is to assess differences in QT interval length between MCG and ECG. The primary safety objective is to characterize the safety profile of the CardiAQ MCG device.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

1. Age ≥ 18 years on the date of consent
2. Ability for participant to comply with study requirements
3. Written informed consent
4. Confirmed diagnosis of atrial fibrillation and receiving dofetilide for rhythm control in the inpatient setting.

Exclusion Criteria

1. Pregnant or breastfeeding
2. Active thoracic metal implants (including pacemaker, insertable cardiac monitor, or internal defibrillators).
3. External electrical pads or devices (e.g. Pacer pads, ECG electrodes, heart rate patch), that must remain on patient's chest during MCG scan
4. Inability to lie down in a supine/inclined position and stay still on the examination bed
5. Clinical conditions that in the opinion of the Investigator would compromise the safety of the patient or ability to complete the protocol

Trial design

100 participants in 1 patient group

Subjects diagnosed with atrial fibrillation

Treatment:

Diagnostic Test: Magnetocardiography