Measles, Mumps, and Rubella (MMR) Immunity in College Students

Sri Edupuganti, MD MPH

Status: Completed

Conditions: Rubella; Mumps; Measles

Treatments: Biological: MMR vaccine

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00962819

IRB00007373

Details and patient eligibility

About

This study will lay the foundation for determining the underlying reasons for lack of immunity to mumps that led to the 2006 mumps outbreak on college campuses in the Mid West, and it will assess the potential for similar outbreaks of measles and rubella. A total of 70 to 80 college students (age 18 to 22) on the Emory campus (or nearby college campuses or the community) will be assessed for antibodies to measles, mumps or rubella by drawing a one-time blood sample. Their medical records will be verified for documentation of immunization with MMR vaccine prior to enrollment in the study. If a study volunteer is found to not have MMR immunity, they will be offered an MMR-II vaccine. For this group, additional blood specimens will be obtained.

Full description

No additional description needed.

Enrollment: 74 patients

Sex: All

Ages: 18 to 24 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Ability and willing to provide an informed consent
• Documented receipt of MMR-II vaccination in childhood
• Not pregnant

Exclusion Criteria

• No history of HIV infection.
• Immunocompromised health status due to HIV infection, cancer, diabetes, liver, lung or kidney diseases, autoimmune diseases, history of splenectomy.
• Use of immunosuppressive medications within last 2 to 3 months (oral or parenteral corticosteroids or cytotoxic medications)
• Medical conditions that require the use of immunosuppressive medications
• Received blood or blood products within the last 30 days
• Any vaccines received in the last 30 days

Trial design

74 participants in 1 patient group

cross-sectional

Description:

College-aged students who were immunized with MMR.

Treatment:

Biological: MMR vaccine