Measure of Plasma Tissue Factor to Predict a Venous Thromboembolism in Primitive Cancer of Lung (FT-KBP)

Hopital Foch

Status

Completed

Conditions

Cancer of Lung

Treatments

Other: venous thromboembolism

Study type

Interventional

Funder types

Other

Identifiers

NCT02853188

2014-A00881-46 (Other Identifier)

2014/21

Details and patient eligibility

About

The aim of the study is to evaluate if the plasma activity of the tissue factor at the time of the diagnosis of a lung cancer, before any treatment, or after the treatment of induction (surgery or two first cures of chemotherapy), can be a predictive factor of venous thromboembolism disease in the year which follows the diagnosis, independently of the other parameters.

Enrollment

315 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients of more than 18 years old
Patients with cancer of lung diagnosis carried for less than 2 months and which were not handled yet, either by surgery or by chemotherapy, or by radiotherapy
Patients whose life expectancy is considered 3-month-old a superior
Patients having given writed consent
Patients affiliated to a national insurance scheme or benefiting from such a diet
Patients having received a treatment (processing) anticoagulating in preventive dose if this treatment was stopped at least 3 days before the 1st taking or patients not receiving an anticoagulating treatment (in case of curative treatment, the latter was before arrested at least 3 months

Exclusion criteria

Patients having a hepatic disease with coagulation disorders
Patients under anticoagulants with dose guardian in 3 months preceding the study or presenting an active infection
Patients having a history of other cancer considered as cured and diagnosed for less than 5 years (with the exception of the patients operated for an in situ carcinoma of the neck of the womb or the patients having undergone the excision of a squamous-cell carcinoma)