Measurement and Analysis of Gas Composition in Digestive Tract

Xiuli Zuo

Status

Not yet enrolling

Conditions

Irritable Bowel Syndrome

Functional Dyspepsia

Helicobacter Pylori Infection

Colorectal Neoplasms

Inflammatory Bowel Diseases

Treatments

Other: gas component of digestive tract

Study type

Observational

Funder types

Other

Identifiers

NCT05810805

2023SDU-QILU-G001

Details and patient eligibility

About

The purpose of this study is to detect the concentration of various gases，including hydrogen, methane, hydrogen sulfide, nitric oxide in different parts of the digestive tract by a safe and direct method, and to establish a human digestive tract gas profiles. Analyze the differences in gas components in different segments of the digestive tract in patients with different diseases, and analyze the correlation between specific gases and digestive tract diseases and non-specific symptoms.

Enrollment

460 estimated patients

Sex

All

Ages

18 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Patients aged 18 to 70 years.
Patients undergoing endoscopic examination

Exclusion criteria

Patients with serious underlying diseases, such as liver insufficiency, renal insufficiency, immunosuppression, coronary heart disease (angina pectoris or coronary artery stenosis ≥ 75%).
Patients have history of gastrointestinal surgery
Patients who failed to complete the endoscopic examination due to various reasons
Patients Boston score of Bowel preparation≤ 6 points
Patients who have medication history of probiotics, antibiotics, PPIs and prokinetic drugs in the last 4 weeks
Patients who combined with thyroid disease and other diseases that affect gastrointestinal motility
Patients who combined with other risk factors such as mental illness, alcoholism, and drug abuse
Patients who unable or unwilling to provide informed consent