Measurement and Modification of Threat Interpretation Bias in Neurodegenerative Movement Disorders (Aims 2 & 3)

University of Virginia

Status: Completed

Conditions: Parkinson Disease; Huntington Disease

Treatments: Behavioral: MindTrails

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05126862

KL2TR003016 (U.S. NIH Grant/Contract)

HSR 210113

Details and patient eligibility

About

The purpose of this study is conduct a pilot open trial of a web-based cognitive bias modification intervention to reduce anxiety symptoms in persons with Huntington's disease and persons with Parkinson's disease.

Full description

After being informed about the study and giving informed consent, participants will enroll in a pilot open trial of MindTrails, a web-based cognitive bias modification intervention. Participants will complete five, 20-minute MindTrails training sessions over five weeks. Additionally, assessments of anxiety, interpretation bias, and other related outcomes will be completed at baseline, week 3, week 5, and 2 months following the last training session. Participants will each complete a semi-structured interview to provide qualitative feedback about their experiences with MindTrails and anxiety.

Enrollment: 43 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of Huntington's disease or Parkinson's disease
• Age 21 or older
• Has anxiety symptoms (NeuroQoL Anxiety short form >12)

Exclusion criteria

• Unable to read and understand English
• Previously diagnosed with dementia
• Not located in the USA

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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43 participants in 1 patient group

MindTrails pilot

Experimental group

Description:

This intervention involves completion of five, 20-minute MindTrails online training sessions over five weeks.

Treatment:

Behavioral: MindTrails