Measurement of in Vivo Mitochondrial Capacity in Infants

Pennington Biomedical Research Center

Status: Terminated

Conditions: Healthy Infants

Study type: Observational

Funder types: Other

Identifiers

NCT03976596

PBRC 2018-051

Details and patient eligibility

About

The overarching aim of this project is to determine the test re-test reliability of 31P-magnetic resonance spectroscopy measurements in infants. Primary endpoints include two separate measures of in vivo mitochondrial capacity (ATPmax) over a 1-10 day period to assess feasibility and reliability.

Enrollment: 2 patients

Sex: All

Ages: 14 to 28 days old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy, full-term infant
• aged 14-28 days at Visit 1
• willingness of parents to be notified of incidental findings from study procedures

Exclusion criteria

• born preterm
• implanted metal or electronic objects that render MRI unsafe
• unable to complete 2 clinic visits 1-10 days apart at Pennington Biomedical Research Center