Measurement of Retinal Venous Pressure Under Short-term Low-oxygen Environment

University Hospital Basel

Status: Completed

Conditions: Healthy

Study type: Observational

Funder types: Other

Identifiers

NCT01771757

USB-2011-327

Details and patient eligibility

About

The hypothesis is that the pressure in the retinal veins increases under a short-term lack of oxygen and leads to a decreased blood circulation. On the basis of measurements in the hypobaric chamber this hypothesis should be verified.

Full description

Conduct a pilot study to describe and quantify the retinal venous pressure (RVP) in healthy volunteers under conditions of controlled, reduced ambient and oxygen partial pressure in the pressure chamber of the Aeromedical Institute FAI in Dübendorf, Switzerland. Obtaining evidence of the adaptation behavior of the retinal vascular system in controlled, short-term hypoxic changes.

Enrollment: 24 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy

Exclusion criteria

• eye diseases
• systemic diseases
• term medication (except contraceptives)
• pregnancy
• allergies to the ingredients Alcain, Tropicamide and Phenylephrine
• blood pressure levels except standard (<60 /> 140 mmHg)
• oxygen saturation (SO2) <90%