Measurement of Serum Potassium Rate During Accidental Hypothermia. (Kai+)

Grenoble Alpes University Hospital Center (CHU)

Status: Unknown

Conditions: Hyperkalemia; Cardiac Arrest; Accidental Hypothermia

Treatments: Diagnostic Test: blood draw from three different vessels

Study type: Interventional

Funder types: Other

Identifiers

NCT03096561

N° ID-RCB: 2016-A01762-49

Details and patient eligibility

About

Serum Potassium Rate (PR) is a key indicator for medical management of patients with accidental hypothermia particularly for hypothermia related cardiac arrest (CA).

Experts recommend a cut-off value for PR of 12 mmol/l for all hypothermic victims and 8 mmol/l for avalanche casualties. Any patient presenting a PR lower than the cut-off value should be considered for Extracorporeal Rewarming. This therapeutic strategy is vital for patient survival.

However, there is no consensus about what type of vessels should be punctured in order to obtain an accurate potassium rate and what type of measurement technics should be used to measure this potassium rate.

The investigators hypothesize that potassium rate in these patients will differ by 1 mmol/l in blood samples collected from a peripheral vein in contrast to a central vein.

The investigators study is a prospective observational, multicentre study.

Enrollment: 12 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Hypothermia related cardiac arrest
• Age > 18 years
• Core temperature < 30° C measured in oesophagus at hospital admission

Exclusion criteria

• Age < 18 years
• Known condition of pregnancy or breastfeeding women
• Evidence of trauma-related cardiac arrest
• Cardiac arrest in which reanimation is not justified (frozen body, final stadium of an incurable disease, advance health care directive)

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

Hypothermia related cardiac arrest

Other group

Description:

blood draw from three different vessels punctured in the emergency room (central vein, peripheral vein, artery) and comparison of potassium rate and other biological values between the different sites of blood draw and two different measuring techniques (laboratory vs. blood gas analyser)

Treatment:

Diagnostic Test: blood draw from three different vessels