Measurements Of Zinc Concentration On Specimens Taken During Trans-Perineal Prostate Biopsy

ProSight

Status: Completed

Conditions: Prostate Cancer

Treatments: Other: prostate biopsy

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01915316

TP001

Details and patient eligibility

About

The purposes of this study are to: i) confirm and improve the accuracy of the correlation between levels of Zinc in prostate tissue and the grade of prostate cancer in that tissue as determined through pathology; and ii) determine the levels of zinc in prostate tissue declared as non-cancerous by pathology and located in the vicinity of tissue declared as cancerous by pathology, and verify that the Zinc levels for the declared non-cancerous tissue are lower (statistically significantly) than the levels for benign tissue not in the vicinity of cancerous tissue.

Enrollment: 30 patients

Sex: Male

Ages: 45+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elevated PSA, >10ng/mL
• Subject underwent primary and at least one secondary (repeat) prostate biopsy with negative diagnosis
• Subject directed at saturated trans-perineal biopsy

Exclusion criteria

• Subject was under Zn supplement nutrition treatment

Trial design

30 participants in 1 patient group

Prostate cancer

Description:

Men. Subjects have undergone primary and at least one secondary prostate biopsy with negative diagnostics. Elevated PSA (Prostate Specific Antigen), typically above 10 ng/mL.

Treatment:

Other: prostate biopsy