Measuring Cardiovascular Performance and Blood Flow Using Common But Never Compared Methods.

Semler Scientific

Status: Completed

Conditions: D001775; D012039

Treatments: Diagnostic Test: No intervention

Study type: Observational

Funder types: Industry

Identifiers

NCT04553484

35-0102

Details and patient eligibility

About

Measuring Cardiovascular Performance Using Common Methods in subjects.

Full description

This study will conduct measurements of cardiovascular performance by echocardiography (Echo), Brain Natriuretic Peptide (BNP) blood serum levels and blood flow by volume plethysmography (VP) in subjects who meet the AHA/ACC criteria for screening for peripheral arterial disease (PAD).

Enrollment: 657 patients

Sex: All

Ages: 45+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• At least 50 Patients from New York Heart Association (NYHA) Class 1 (One or more AHA Risk Factors, asymptomatic), ≤75% (36) Male, ≥25% (12) Female
• At least 50 Patients from NYHA Class 2 (symptomatic), ≤75% (36) Male, ≥25% (12) Female

Exclusion criteria

• Subjects on mechanical ventilation.
• Subjects who require decisions by a medical power of attorney.
• Subjects unable to safely perform forced expiration.
• Subjects with known technically difficult (TDS) trans-thoracic echocardiographic windows.

Trial design

657 participants in 1 patient group

All subjects enrolled

Description:

The feasibility of conducting all three tests, echocardiography (Echo), Brain Natriuretic Peptide (BNP) and volume plethysmography (VP), on all subjects met the enrollment criteria.

Treatment:

Diagnostic Test: No intervention