Measuring Corneal Cells With Specular Microscopy

Retina Institute of Hawaii

Status: Completed

Conditions: Retinal Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT01792154

RIH 1011

Details and patient eligibility

About

Assess changes in the corneal cell count using Specular Microscopy following tretments with Anti-VEGF injections

Full description

Patients with active Wet AMD often receive intraocular Anti-VEGF injections such as Macugen, Lucentis and Avastin on a monthly basis for an extended period of time. While these medications are very effective at controlling the Choroidal Neovascularization associated with this disease, the impact of monthly intravigtreal Anti-VEGF injections on the viability of corneal endothelial cells has yet to be fully characterized. The availability of CESM as a diagnostic test that can be performed quickly and painlessly in the clinic offers a method of tracking corneal endothelial cell count in this patient population.

Enrollment: 30 patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Wet Age-related Macular Degeneration
• Receiving monthly intraocular injections of Anti-VEGF medication for at least 3 months
• Age greater than 50 years of age

Exclusion criteria

• experiences adverse events