Measuring Cyclotorsion on Scanning Laser Ophthalmoscopy (SLO)-Fundus Photographs (CySLO)

University of Zurich (UZH)

Status: Completed

Conditions: Trochlear Nerve Diseases

Treatments: Device: Heidelberg Spectralis OCT device

Study type: Interventional

Funder types: Other

Identifiers

NCT02631369

KEK-ZH-Nr. 2014-0404

Details and patient eligibility

About

Pre-Study: Evaluation of the inter- and intrarater reliability of the integrated algorithm by Heidelberg Spectralis for measuring cyclotorsion on SLO-fundus fotographs, and assessment of the influence of measuring with or without eye tracker.

Study: Comparison of cyclotorsion measurements in patients with forth nerve palsy and in healthy controls on SLO-fundus fotographs using the integrated algorithm by Heidelberg Spectralis

Enrollment: 82 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ≥ 18 years old
• best corrected visual acuity ≥ 0.8

Exclusion criteria

• strabismus except for forth nerve palsy
• previous strabismus surgery
• monocle
• best corrected visual acuity ≤ 0.6
• hyperopia or myopia > 6dpt

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

82 participants in 3 patient groups

inter- & intrarater reliability study

Experimental group

Description:

pre-study: inter- and intrarater reliability study in 30 healthy subjects, interventions: SLO-fundus photographs using the integrated algorithm by Heidelberg Spectralis OCT (optical coherence tomography) device

Treatment:

Device: Heidelberg Spectralis OCT device

cyclotorsion in forth nerve palsy

Experimental group

Description:

measurement of cyclotorsion on SLO-fundusphoto in 20 patients forth nerve palsy interventions: SLO-fundus photographs using the integrated algorithm by Heidelberg Spectralis OCT (optical coherence tomography) device

Treatment:

Device: Heidelberg Spectralis OCT device

cyclotorsion in healthy subjects

Experimental group

Description:

measurement of cyclotorsion on SLO-fundusphoto in 30 healthy subjects to be compared to patients with forth nerve palsy interventions: SLO-fundus photographs using the integrated algorithm by Heidelberg Spectralis OCT (optical coherence tomography) device

Treatment:

Device: Heidelberg Spectralis OCT device