Measuring the Changes of the Intraocular Pressure After Corneal Cross Linking Using Corvis CT

Tanta University

Status: Begins enrollment this month

Conditions: Keratoconus; Intraocular Pressure

Treatments: Device: Corvis Machine

Study type: Interventional

Funder types: Other

Identifiers

NCT07599020

36264PR131099/12/25

Details and patient eligibility

About

To evaluate the changes that occur in the intraocular pressure before and after corneal cross linking using Corvis CT.

Full description

This study will be prospective study. 50 Patients will be included who will undergo corneal cross linking from the out-patient clinic of Tanta University hospital between December 2025 and December 2026 will be included in the study .

Patient with age 19 till 35 years old will be included

Patient with Corneal scarring, Previous corneal infections, Minimum corneal thickness at the thinnest location less than 400 µm, History of uveitis or ocular allergy and Pre-existing glaucoma will be excluded from the study

All patient will undergo full ophthalmological examination. including best corrected visual acuity, degree of myopia , average kertometry and intraocular pressure will be measured before and after cross linkage with three different techniques including Shiotz tonometry, appalanation tonometry and CORVIS machine

Enrollment: 1 estimated patient

Sex: All

Ages: 19 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients who will corneal cross linking for mild degree of keratoconus, age between 19 and 35 years old

Exclusion criteria

• Corneal scarring.
• Previous corneal infections.
• Minimum corneal thickness at the thinnest location less than 400 µm.
• History of uveitis or ocular allergy.
• Pre-existing glaucoma.

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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1 participants in 1 patient group

Measuring the intraocular pressure after cross linking

Other group

Description:

Measuring the intraocular pressure by using different techniques after corneal cross linking

Treatment:

Device: Corvis Machine