Measuring the Electrical Properties of Malignant Tissues Ex Vivo

S

Southern Medical University

Status

Unknown

Conditions

Neoplasms

Treatments

Device: network analyzer

Study type

Observational

Funder types

Other

Identifiers

NCT02747212
SXXin-EPs-measurement-ex vivo

Details and patient eligibility

About

Previously published studies have indicated that there exist difference in electrical properties (EPs), i.e., the conductivity and relative permittivity, between malignant and adjacent normal tissue, which will be useful in the early detection of cancers. While the EP informations of cancer tissues are not sufficient enough. The purpose of this study is to measure the electrical properties of the excised malignant tissues obtained from cancer surgeries.

Full description

The measurements were conducted in the operating rooms of the hospital where the tissues were excised. Once the tissue was excised from the patient, the pathologist assisted the one of the engineers (already at the hospital) responsible to conduct the measurement. The specimen were designed to permit at least one measurement of malignant tissue and at least one measurement of normal tissue. Occasionally, the measurement of normal tissue was not possible if, for example, the normal tissue occupied a volume of small proportion for every excised specimen. The specimens for dielectric properties measurement were classified as normal or malignant by the pathologist based on his own expertise and decision criteria (visual inspection, anatomy) and the per-operative histological examination. The measurements were directly performed on the bulk specimen. The patient age, tissue temperature at the time of measurement and time between excision and measurement for each sample were recorded.

Enrollment

200 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

Clinical diagnosis of cancer Disease

Exclusion criteria

None

Trial contacts and locations

1

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Central trial contact

Sherman X Xin, professor

Data sourced from clinicaltrials.gov

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