Measuring the Impact of Integrating Maternal and Newborn HIV Testing With Childhood Immunization Services

IDinsight

Status: Completed

Conditions: HIV

Treatments: Other: Policy reinforcement meeting; Other: Operational support for service integration; Other: HIV testing commodity reinforcement; Other: Opt-out HIV testing for mothers and newborns; Other: Community sensitization

Study type: Interventional

Funder types: Other

Identifiers

NCT02479659

001

Details and patient eligibility

About

This randomized evaluation measured the impact of two levels of support for the integration of infant and postpartum maternal HIV testing with routine immunization services in Southern Zambia on the number of postpartum maternal HIV tests, infant HIV tests, and 1st dose diphtheria, pertussis, and tetanus (DPT1) vaccines.

Full description

This evaluation assessed two levels of support for the integration of early infant and maternal HIV testing with existing routine immunization services in rural health facilities in Southern Zambia with the aim of determining whether infant and postpartum maternal HIV testing rates would increase without harming immunization uptake. The evaluation randomized 60 health facilities to one of three study arms: 1) Control (status quo); 2) Simple Intervention; and 3) Comprehensive Intervention. The Simple Intervention included restocking of HIV test kits and reminding health facilities of existing HIV testing guidelines by government health officials. The Comprehensive Intervention included the Simple Intervention components, as well as community sensitization, hands-on operational support to integrate services and improve patient flow, and opt-out HIV testing for mothers and infants according to existing guidelines. The change in the average number of monthly HIV tests and immunizations (DPT1) between the intervention period and baseline were compared between treatment and control facilities.

Enrollment: 60 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Note that this evaluation used administrative data - no participants were enrolled for the main part of this study. Participants were enrolled for the qualitative portions of the study.

Inclusion Criteria:

• Mothers who had an infant within the past 18 months during the intervention period (Oct 2013 - Mar 2014)
• Infants who were at least six weeks of age and under six months of age during the intervention period (Oct 2013 - Mar 2014)
• Qualitative activities included facility staff and mothers and caregivers whose infants were due for their 6 week immunization during the intervention period.

Exclusion Criteria:

• Mothers who did not have an infant within the past 18 months during the intervention period
• Infants who were less than six weeks of age during the intervention period or greater than six months of age throughout out the intervention period.
• Adults who were not mothers or caregivers with an infant due for his/her 6 week immunization during the intervention period were excluded from the qualitative activities.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 3 patient groups

Control

No Intervention group

Description:

Facilities in this arm maintained status quo HIV testing and routine childhood immunization services

Simple Intervention

Experimental group

Description:

This included: 1) HIV testing commodity reinforcement and 2) a policy reinforcement meeting

Treatment:

Other: Policy reinforcement meeting

Other: HIV testing commodity reinforcement

Comprehensive Intervention

Experimental group

Description:

This arm included: 1) HIV testing commodity reinforcement, 2) a policy reinforcement meeting, 3) community sensitization, 4) Opt-out HIV testing for mothers and newborns, and 5) Operational support for service integration

Treatment:

Other: Community sensitization

Other: Opt-out HIV testing for mothers and newborns

Other: Operational support for service integration

Other: Policy reinforcement meeting

Other: HIV testing commodity reinforcement