Mechanical Alternans Study (MAS)

Johns Hopkins University

Status: Completed

Conditions: Heart Failure; Nonischemic Cardiomyopathy; Ischemic Cardiomyopathy

Study type: Observational

Funder types: Other

Identifiers

NCT01557465

NA_00032758

Details and patient eligibility

About

The purpose of this study is to determine whether mechanical alternans (alternating strong and weak heart beats with a constant beat-to-beat interval), can be used to predict malignant ventricular arrhythmias, requiring defibrillation or appropriate ICD therapies, and to predict progression of heart failure and death.

Enrollment: 134 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• structural heart disease
• ischemic or non-ischemic cardiomyopathy

Exclusion criteria

• pregnancy
• age < 18 years old