Mechanism and Predictor of Side Branch Jailing (PRESSURE)

Seoul National University

Status: Completed

Conditions: Main Branch Stent Implantation; Bifurcating Coronary Artery Lesions; Side Branch Jailing

Study type: Observational

Funder types: Other

Identifiers

NCT00553670

H-0707-022-212

Details and patient eligibility

About

Coronary artery bifurcation lesion is still one of the most challenging lesion subsets in the field of non-surgical treatment for a stenotic coronary artery. When one stent is placed in the main brach, it increases the side branch's stenosis degree. However, its mechanism and incidence are not known. This study will be performed to search for the mechanism and incidence of that phenomenon.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Elective coronary intervention (including stabilized ACS patients)
2. Bifurcation lesion with TIMI 3 flow
3. Side branch diameter > 2mm, side branch lesion length < 10mm by visual estimation

Exclusion criteria

1. Left main coronary disease
2. AMI, or Old MI at LAD territory
3. LVEF < 40%, or other significant valvular or myocardial disease
4. Significant side branch distal lesion
5. Angiographically visible thrombus
6. Heavily calcified lesion
7. Side branch predilatation before main branch stent implantation

Trial design

100 participants in 1 patient group

1

Description:

Patients with elective coronary intervention for LAD-diagonal bifurcation lesion with provisional side branch intervention strategy with successful intravascular ultrasound and fractional flow reserve measurement