Mechanisms of Exercise-Induced Hypoalgesia

University of Central Florida

Status: Completed

Conditions: Healthy

Treatments: Other: Negative Expectations Instructional Set; Other: Positive Expectations Instructional Set

Study type: Interventional

Funder types: Other

Identifiers

NCT06050889

6

Details and patient eligibility

About

Exercise-Induced Hypoalgesia (EIH) is a lessening of pain sensitivity in response to an acute bout of exercise. Limited research has examined the effects of expectations on EIH during a dynamic resistance training during different intensities. Therefore, the purpose of this study is to examine the effects of positive and negative expectations on EIH.

Full description

Individuals who meet the eligibility criteria and consent to participate will attend one testing session that is approximately one hour. Baseline Pressure Pain Threshold will be measured followed by random assignment to one of four study arms.

Enrollment: 60 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pain Free

Exclusion criteria

• Non-English speaking
• Regular use of prescription pain medications
• Current or history of chronic pain condition
• Currently taking blood-thinning medication
• Any blood clotting disorder, such as hemophilia
• Systemic medical condition known to affect sensation, such as uncontrolled diabetes or neurological conditions
• Not physically ready to exercise without a medical exam as indicated by the Physical Activity Readiness Questionnaire Plus (PAR-Q+)
• Not have had Surgery, injury, or fracture within the past 6 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

High Intensity Exercise

Experimental group

Description:

Participants will complete an upper body resistance exercise until they report a high fatigue level.

Treatment:

Other: Positive Expectations Instructional Set

Other: Negative Expectations Instructional Set

Low Intensity Exercise

Experimental group

Description:

Participants will complete an upper body resistance exercise until they report a low fatigue level.

Treatment:

Other: Positive Expectations Instructional Set

Other: Negative Expectations Instructional Set