Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers

University Hospital, Angers

Status

Completed

Conditions

Healthy Volunteers

Treatments

Drug: sodium nitroprusside

Drug: emla

Drug: indomethacin

Drug: brethyllium

Drug: clopidogrel

Device: pressure strain system, iontophoresis

Drug: aspirin

Drug: capsaicin

Drug: celecoxib

Drug: scopolamin

Device: general and local heating

Drug: acetylcholine

Study type

Observational

Funder types

Other

Identifiers

NCT00152724

CP96-04

Details and patient eligibility

About

Microvascular dysfunctions are critical events in several diseases including diabetes. This study will develop a methodology for microvascular investigation in human skin. The purpose of the study is to investigate the physiological response of the cutaneous microcirculation to physical, thermal, mechanical or chemical stimulations.

Full description

This study has investigated various aspects of the physiology of the microcirculation in the past years and is still recruiting under parallel protocols of physiological investigations of the neurovascular control of the cutaneous microcirculation.

Enrollment

85 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria