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Mechanisms of Severe Acute Influenza Consortium (MOSAIC)

Imperial College London logo

Imperial College London

Status

Completed

Conditions

Influenza

Study type

Observational

Funder types

Other

Identifiers

NCT00965354
09/H0709/52 (Other Identifier)
09/MRE00/67 (Other Identifier)
CRO1367

Details and patient eligibility

About

The ultimate goal of this collaborative, intensive study is to discover new and effective treatments and to develop better vaccines that can be used in future outbreaks of Influenza A. By integrating the information that we will gather, we will create a unique overview of how influenza causes illness and what might be done to improve patient management.

Full description

Influenza A is one of the best studied viruses, but continues to have a very large impact on human and animal health. In addition to causing outbreaks of winter flu, it sometimes mutates to create a new virus that spreads quickly around the world. It is puzzling that the same virus appears to cause minor or absent symptoms in some people while killing others. Much remains to be understood.

The investigators have assembled an unprecedented group of internationally renowned scientists from England and Scotland who will together focus on studying a few hundred people hospitalised during the current swine flu pandemic. Such a large scale project has never before been attempted, but we are now poised to work together and integrate the many recent advances in biomedical science that relate to understanding how influenza causes disease.

Enrollment

131 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Any patient admitted to hospital with suspected or confirmed influenza infection

Exclusion criteria

  • Patients who do not give their consent

Trial design

131 participants in 1 patient group

Influenza diagnosis
Description:
Patients admitted to hospital with a suspected or confirmed influenza diagnosis on admission

Trial contacts and locations

8

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Data sourced from clinicaltrials.gov

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